For more information: https://hpets.org/index.php
· Clindamycin (Antirobe) [11-22mg/kg twice daily
· Potentiated sulphonamides (e.g. Tribissen Co-Trimoxazole) [15mg/kg twice daily]
· Pyrimethamine (Daraprim ,anti-malarial drug) [1mg.kg once daily]
Treatment should be instituted as soon as possible when neosporosis is suspected. Since the drugs have few side effects and are relatively cheap, this might even be before serological test results are available. If the dog is going to respond, there should be some improvement within a few days of commencing treatment Treatment should continue until the dog has fully recovered or no further clinical improvement is seen (2-9 weeks). Supportive treatment, e.g. aspirin like drugs, low doses of corticosteroids, plus good nursing care e.g. bladder expression and physiotherapy are also beneficial.
About half of appropriately treated dogs might be expected to make a full or functional recovery, although many are left with an odd gait, muscle wastage or roached back. Rigid hyperextension is the sign least likely to be reversed. If this hyperextension is unilateral, amputation of the affected limb may improve the dogs mobility. Peracute and very chronic cases are the least likely to respond.
There is anecdotal evidence that relapses may occur, but these generally respond well to a further short course of treatment
There is also evidence that some, generally more mildly affected, dogs make a spontaneous recovery.
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Korean J Parasitol. 2003 Mar;41(1):1-16. Related Articles, Links
· Korean J Parasitol. 2003 Jun;41(2):138. Dubey John P [corrected to Dubey J P]
Review of Neospora caninum and neosporosis in animals.
United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Beltsville Agricultural Research Center, Building 1001, Beltsville, Maryland, 20705-2350, USA. firstname.lastname@example.org
Neospora caninum is a coccidian parasite of animals. It is a major pathogen for cattle and dogs and it occasionally causes clinical infections in horses, goats, sheep, and deer. Domestic dogs are the only known definitive hosts for N. caninum. It is one of the most efficiently transmitted parasite of cattle and up to 90% of cattle in some herds are infected. Transplacental transmission is considered the major route of transmission of N. caninum in cattle. Neospora caninum is a major cause of abortion in cattle in many countries. To elicit protective immunity against abortion in cows that already harbor a latent infection is a major problem. This paper reviews information on biology, diagnosis, epidemiology and control of neosporosis in animals.
· Review, Tutorial
PMID: 12666725 [PubMed - indexed for MEDLINE]
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I am so happy that you have found another avenue to pursue. And scratching with a leg is very definitely a positive thing! We are hoping for you and Mariah and wishing you the best of luck with your holistic approach. Please keep us posted on how you and Mariah are doing!